Can an RTX 3080 10GB run Qwen2.5 14B Instruct?

Yes

Yes. At Q3_K_M it needs 9.14 GB of the 9.2 GB available and generates around 75.8 tokens per second at an 8k context window.

The numbers

Qwen2.5 14B Instruct has 14.77 billion parameters across 48 layers. The GeForce RTX 3080 10GB has 10 GB of VRAM at 760 GB/s, of which about 9.2 GB is left for a model once the operating system has taken its share.

QuantisationTotal neededFitsSpeed
Q8_0 17.03 GB no
Q6_K 13.69 GB no
Q5_K_M 12.2 GB no
Q4_K_M 10.72 GB no
IQ4_XS 9.72 GB no
Q3_K_M 9.14 GB yes 75.8 t/s
IQ3_XXS degraded 7.68 GB yes 92.2 t/s
Q2_K degraded 8.17 GB yes 85.8 t/s
IQ2_XXS degraded 5.96 GB yes 123.6 t/s

4 of the 9 levels fit. Levels marked degraded are listed for completeness, not as advice.

How long a conversation it holds

At Q3_K_M, memory rises with the length of the conversation because the attention cache keeps a key and value for every token. The longest window that still fits on this device is 8k tokens.

ContextCacheTotalFits
4k 0.75 GB 8.23 GB yes
8k 1.5 GB 9.14 GB yes
16k 3 GB 10.95 GB no
32k 6 GB 14.57 GB no

See how fast it feels

GeForce RTX 3080 10GB running Qwen2.5 14B Instruct at Q3_K_M

Wait for the first word334 ms
Then writes at75.8 tok/s
Whole answer2.6 s

YouWhy does my model use more memory when the conversation gets longer?

Model

Because of the KV cache. Every token you send leaves behind a key and a value vector in each layer of the model, and those stay in memory for as long as the conversation lasts.

The weights are a fixed cost: load a 4-bit 8B model and that is about 4.8 GB, whether you write one word or ten thousand. The cache is the part that grows, and it grows in a straight line with the number of tokens in the window.

How steeply depends on the model's attention design. With grouped-query attention, several query heads share one key-value pair, which cuts the cache by that ratio. Without it, every head keeps its own, and a long context can cost more memory than the weights themselves.

If you are short on memory, the first thing to try is lowering the context window in your runtime, not the quantisation.

Simulated from our estimate at a 512-token question, not a recording. Assumes nothing else is competing for the GPU. The same answer on RTX 4090 at Q8_0 would take about 3.5 s.

Keep going

Everything the GeForce RTX 3080 10GB runs, the full breakdown for Qwen2.5 14B Instruct, or check a different pairing in the calculator.